Posted by: I.I. Vorobіova, S.M. Tolkach, V.B. Tkachenko,A.A. Zhyvetska-Denysova, N.V. Rudakova.
Institute of Pediatrics, obstetrics and gynecology named after Academician О. M. Lukyinic NAMS of Ukraine.
Place of publication:
Reproductive Health. Eastern Europe. 2019, Volume 9, № 3.
Pregnancy miscarriage is one of the major medical and social problems in obstetric practice, perinatal medicine and public health in general. The great importance and widespread use of progesterone during pregnancy have led scientists to invent a new, highly effective, bioavailable and easy to use a form of this hormone – micronisation. The results of the work proved that the clinical use, according to the indications, of these forms of progestins during pre-gravidar drug and the direct course of pregnancy is an effective means of prevention and treatment of certain forms of miscarriage. As micronized progesterone, the drugs Proginorm GESTA and Proginorm OVO, adapted for, respectively, vaginal and oral administration were used. In our opinion, the presence of forms of the drug adapted to a certain environment (vaginal mucosa – Proginorm GESTA and mucous membrane of the gastrointestinal tract - Proginorm OVO) makes it possible to make maximum use of its pharmacological properties, which differs favourably from analogues.
Keywords: miscarriage, progesterone micronized, Proginorm GESTA, Proginorvo OVO.