Summary. The article is devoted to the treatment of patients with chronic recurrent pain in the lower back. The data of a study of the clinical efficacy and safety of the drug Artrida ® are presented, the use of which in complex therapy at the time of exacerbation and the presence of topical pain syndrome allowed to reduce the time and dose of non-steroidal anti-inflammatory drugs, and also helped to improve the biomechanical parameters and functional ability of patients.